Acute vs Delayed Iron Therapy PI: Cusick
Acute vs Delayed Iron: Effect On Red Cell Iron Incorporation In Severe Malaria
Iron deficiency anemia blood film. Image by Dr. Graham Beard via Wiki Commons
One quarter of the world's population does not have adequate blood iron. Globally, iron deficiency and malaria are primary contributors to this statistic, and where the conditions coexist, the resulting anemia is often severe and disproportionately affects young children. However, iron supplementation can enhance the growth of malaria parasites in these young children.
The hypothesis is that delaying iron supplementation in children until 4 weeks post antimalarial treatment could both reduce the immediate morbidity and mortality in this age group and ensure the full neurobehavioral development of millions of iron-deficient children who live in malaria-endemic regions of the world.